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1

Stable isotope-resolved metabolomics and applications for drug development

Teresa W.-M. Fan, Pawel K. Lorkiewicz, Katherine Sellers, Hunter N.B. Moseley, Richard M. Higashi, Andrew N. Lane

Journal:

Pharmacology & Therapeutics

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

2

[Methods in Pharmacology and Toxicology] The Handbook of Metabolomics ||

Fan, Teresa Whei-Mei, Lane, Andrew N., Higashi, Richard M.

Year:

2012

Language:

english

File:

PDF, 11.09 MB

english, 2012

3

Nitric oxide orchestrates metabolic rewiring in M1 macrophages by targeting aconitase 2 and pyruvate dehydrogenase

Palmieri, Erika M., Gonzalez-Cotto, Marieli, Baseler, Walter A., Davies, Luke C., GhesquiÃ¨re, Bart, Maio, Nunziata, Rice, Christopher M., Rouault, Tracey A., Cassel, Teresa, Higashi, Richard M., Lane

Journal:

Nature Communications

Year:

2020

Language:

english

File:

PDF, 1.88 MB

english, 2020

4

Comprehensive Analysis of Organic Ligands in Whole Root Exudates Using Nuclear Magnetic Resonance and Gas Chromatography–Mass Spectrometry

Teresa W.-M. Fan, Andrew N. Lane, Judy Pedler, David Crowley, Richard M. Higashi

Journal:

Analytical Biochemistry

Year:

1997

Language:

english

File:

PDF, 261 KB

english, 1997

5

Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions

Teresa W.-M. Fan, Peixiong Yuan, Andrew N. Lane, Richard M. Higashi, Yun Wang, Anahita B. Hamidi, Rulun Zhou, Xavier Guitart, Guang Chen, Husseini K. Manji, Rima Kaddurah-Daouk

Journal:

Year:

2010

Language:

english

File:

PDF, 1.07 MB

english, 2010

6

[Methods in Pharmacology and Toxicology] The Handbook of Metabolomics || Metabolomic Applications of Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Fan, Teresa Whei-Mei, Lane, Andrew N., Higashi, Richard M.

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

7

Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry

Gori, Sadakatali S., Lorkiewicz, Pawel, Ehringer, Daniel S., Belshoff, Alex C., Higashi, Richard M., Fan, Teresa W.-M., Nantz, Michael H.

Journal:

Analytical and Bioanalytical Chemistry

Year:

2014

Language:

english

File:

PDF, 790 KB

english, 2014

8

Integrating Metabolomics and Transcriptomics for Probing Se Anticancer Mechanisms*

Fan, Teresa W.-M., Higashi, Richard M., Lane, Andrew N.

Journal:

Drug Metabolism Reviews

Year:

2006

Language:

english

File:

PDF, 695 KB

english, 2006

9

Metabolomics Workbench: An international repository for metabolomics data and metadata, metabolite standards, protocols, tutorials and training, and analysis tools

Sud, Manish, Fahy, Eoin, Cotter, Dawn, Azam, Kenan, Vadivelu, Ilango, Burant, Charles, Edison, Arthur, Fiehn, Oliver, Higashi, Richard, Nair, K. Sreekumaran, Sumner, Susan, Subramaniam, Shankar

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 2.32 MB

english, 2015

10

Official American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America Clinical Practice Guidelines: Treatment of Drug-Susceptible Tuberculosis

Nahid, Payam, Dorman, Susan E., Alipanah, Narges, Barry, Pennan M., Brozek, Jan L., Cattamanchi, Adithya, Chaisson, Lelia H., Chaisson, Richard E., Daley, Charles L., Grzemska, Malgosia, Higashi, Juli

Journal:

Clinical Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 1.01 MB

english, 2016

11

Exploring Cancer Metabolism using Stable Isotope Resolved Metabolomics (SIRM)

Bruntz, Ronald C., Lane, Andrew N., Higashi, Richard M., Fan, Teresa W-M.

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 454 KB

english, 2017

12

Parent-Provider Communication of HPV Vaccine Hesitancy

Shay, Laura A., Baldwin, Austin S., Betts, Andrea C., Marks, Emily G., Higashi, Robin T., Street, Richard L., Persaud, Donna, Tiro, Jasmin A.

Journal:

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

13

Localization of LRRK2 to membranous and vesicular structures in mammalian brain

Saskia Biskup, Darren J. Moore, Fulvio Celsi, Shinji Higashi, Andrew B. West, Shaida A. Andrabi, Kaisa Kurkinen, Seong-Woon Yu, Joseph M. Savitt, Henry J. Waldvogel, Richard L. M. Faull, Piers C. Emso

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 12.84 MB

english, 2006

14

Sorption–desorption behavior of phenanthrene elucidated by pyrolysis–gas chromatography-mass spectrometry studies of soil organic matter

Liese F. Schultz, Thomas M. Young, Richard M. Higashi

Journal:

Environmental Toxicology and Chemistry

Year:

1999

Language:

english

File:

PDF, 170 KB

english, 1999

15

Stable isotope-assisted metabolomics in cancer research

Andrew N. Lane, Teresa W.-M. Fan, Richard M. Higashi

Journal:

Year:

2008

Language:

english

File:

PDF, 222 KB

english, 2008

16

Sublethal effects of pentachlorophenol in the abalone (haliotis rufescens) as measured by in vivo 31P NMRSpectroscopy

Ronald S. Tjeerdema, Teresa W.-M. Fan, Richard M. Higashi, Donald G. Crosby

Journal:

Journal of Biochemical and Molecular Toxicology

Year:

1991

Language:

english

File:

PDF, 1.11 MB

english, 1991

17

Monitoring of metabolic responses of intact Haliotis (abalones) under salinity stress by 31P surface probe localized NMR

Richard M. Higashi, Teresa W.-M. Fan, Jeffrey M. Macdonald

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Year:

1989

Language:

english

File:

PDF, 689 KB

english, 1989

18

Comprehensive chemical profiling of gramineous plant root exudates using high-resolution NMR and MS

Teresa W.-M. Fan, Andrew N. Lane, Moshe Shenker, John P. Bartley, David Crowley, Richard M. Higashi

Journal:

Year:

2001

Language:

english

File:

PDF, 1.62 MB

english, 2001

19

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on13C mass isotopologue profiles under non-steady-state conditions

Hunter NB Moseley, Andrew N Lane, Alex C Belshoff, Richard M Higashi, Teresa WM Fan

Journal:

Year:

2011

Language:

english

File:

PDF, 2.25 MB

english, 2011

20

An electrophoretic proﬁling method for thiol-rich phytochelatins and metallothioneins

Teresa W-M. Fan, Andrew N. Lane, Richard M. Higashi

Journal:

Phytochemical Analysis

Year:

2004

Language:

english

File:

PDF, 233 KB

english, 2004

21

Metabolomics-edited transcriptomics analysis of Se anticancer action in human lung cancer cells

Teresa W. M. Fan, Laura L. Bandura, Richard M. Higashi, Andrew N. Lane

Journal:

Year:

2005

Language:

english

File:

PDF, 944 KB

english, 2005

22

Metabolic acidosis and the importance of balanced equations

Andrew N. Lane, Teresa W.-M. Fan, Richard M. Higashi

Journal:

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

23

Stable isotope resolved metabolomics of lung cancer in a SCID mouse model

Teresa W.-M. Fan, Andrew N. Lane, Richard M. Higashi, Jun Yan

Journal:

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

24

Isotopomer analysis of lipid biosynthesis by high resolution mass spectrometry and NMR

Andrew N. Lane, Teresa W.-M. Fan, Zhengzhi Xie, Hunter N.B. Moseley, Richard M. Higashi

Journal:

Analytica Chimica Acta

Year:

2009

Language:

english

File:

PDF, 771 KB

english, 2009

25

Interactive effects of Ca2+ and NaCl salinity on the ionic relations and proline accumulation in the primary root tip of Sorghum bicolor

Timothy D. Colmer, Teresa W.-M. Fan, Richard M. Higashi, André Läuchli

Journal:

Physiologia Plantarum

Year:

1996

Language:

english

File:

PDF, 3.27 MB

english, 1996

26

Helicobacter pylori CagA activates NF-κB by targeting TAK1 for TRAF6-mediated Lys 63 ubiquitination

Lamb, Acacia, Yang, Xiao-Dong, Tsang, Ying-Hung N, Li, Jiang-Dong, Higashi, Hideaki, Hatakeyama, Masanori, Peek, Richard M, Blanke, Steven R, Chen, Lin-Feng

Journal:

Year:

2009

Language:

english

File:

PDF, 745 KB

english, 2009

27

Root exudation and physiological status of a root-colonizing fluorescent pseudomonad in mycorrhizal and non-mycorrhizal pepper (Capsicum annuum L.)

Petra Marschner, David E. Crowley, Richard M. Higashi

Journal:

Year:

1997

Language:

english

File:

PDF, 207 KB

english, 1997

28

The use of Solid Phase MicroExtraction (SPME) devices in analysis for potential mosquito oviposition attractant chemicals from cyanobacterial mats

Eliska Rejmankova, Richard M. Higashi, Donald R. Roberts, Michele Lege, Richard G. Andre

Journal:

Aquatic Ecology

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

29

Bone scintigraphy in detection of bone invasion by oral carcinoma

Kotaro Higashi, Hiromi Wakao, Hiroyuki Ikuta, Isamu Kashima, F. Richard Everhart

Journal:

Annals of Nuclear Medicine

Year:

1996

Language:

english

File:

PDF, 1.54 MB

english, 1996

30

Implanted standards for detection of transition metal contamination of silicon surfaces

D.C. Jacobson, J.M. Poate, G.S. Higashi, T. Boone, Richard Hocket

Journal:

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

Year:

1993

Language:

english

File:

PDF, 368 KB

english, 1993

31

Localization of Parkinson’s disease-associated LRRK2 in normal and pathological human brain

Shinji Higashi, Saskia Biskup, Andrew B. West, Daniel Trinkaus, Valina L. Dawson, Richard L.M. Faull, Henry J. Waldvogel, Heii Arai, Ted M. Dawson, Darren J. Moore, Piers C. Emson

Journal:

Year:

2007

Language:

english

File:

PDF, 1.85 MB

english, 2007

32

Metabolic profiling identifies lung tumor responsiveness to erlotinib

Teresa W.-M. Fan, Andrew N. Lane, Richard M. Higashi, Michael Bousamra II, Goetz Kloecker, Donald M. Miller

Journal:

Experimental and Molecular Pathology

Year:

2009

Language:

english

File:

PDF, 571 KB

english, 2009

33

Prospects for clinical cancer metabolomics using stable isotope tracers

Andrew N. Lane, Teresa W.-M. Fan, Richard M. Higashi, Jinlian Tan, Michael Bousamra, Donald M. Miller

Journal:

Experimental and Molecular Pathology

Year:

2009

Language:

english

File:

PDF, 813 KB

english, 2009

34

Monitoring of hypoxic metabolism in superfused plant tissues by in vivo 1H NMR

Teresa W.-M. Fan, Richard M. Higashi, Andrew N. Lane

Journal:

Archives of Biochemistry and Biophysics

Year:

1986

Language:

english

File:

PDF, 1008 KB

english, 1986

35

An in vivo 1H and 31P NMR investigation of the effect of nitrate on hypoxic metabolism in maize roots

Teresa W-M. Fan, Richard M. Higashi, Andrew N. Lane

Journal:

Archives of Biochemistry and Biophysics

Year:

1988

Language:

english

File:

PDF, 1.30 MB

english, 1988

36

Hypoxia does not affect rate of ATP synthesis and energy metabolism in rice shoot tips as measured by 31P NMR in vivo

Teresa W.-M. Fan, Andrew N. Lane, Richard M. Higashi

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 591 KB

english, 1992

37

Tidal salt marsh sediment in California, USA. Part 2: Occurrence and anthropogenic input of trace metals

Hyun-Min Hwang, Peter G. Green, Richard M. Higashi, Thomas M. Young

Journal:

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

38

The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type

Mariia O. Yuneva, Teresa W.M. Fan, Thaddeus D. Allen, Richard M. Higashi, Dana V. Ferraris, Takashi Tsukamoto, José M. Matés, Francisco J. Alonso, Chunmei Wang, Youngho Seo, Xin Chen, J. Michael Bisho

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 1.94 MB

english, 2012

39

Hippocampal injury and neurobehavioral deficits are improved by PD 81,723 following hyperglycemic cerebral ischemia

Joseph R Meno, Hisato Higashi, Adam J Cambray, Jiegang Zhou, Raimondo D’Ambrosio, H.Richard Winn

Journal:

Experimental Neurology

Year:

2003

Language:

english

File:

PDF, 258 KB

english, 2003

40

Preface

Teresa Fan, Richard Higashi, David E Hinton

Journal:

Aquatic Toxicology

Year:

2002

Language:

english

File:

PDF, 35 KB

english, 2002

41

Selenium biotransformations into proteinaceous forms by foodweb organisms of selenium-laden drainage waters in California

Teresa W.-M Fan, Swee J Teh, David E Hinton, Richard M Higashi

Journal:

Aquatic Toxicology

Year:

2002

Language:

english

File:

PDF, 756 KB

english, 2002

42

Integrating contaminant responses in indicator saltmarsh species

Susan L. Anderson, Gary N. Cherr, Steven G. Morgan, Carol A. Vines, Richard M. Higashi, William A. Bennett, Wendy L. Rose, Andrew J. Brooks, Roger M. Nisbet

Journal:

Marine Environmental Research

Year:

2006

Language:

english

File:

PDF, 101 KB

english, 2006

43

High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS

Lorkiewicz, Pawel, Higashi, Richard M., Lane, Andrew N., Fan, Teresa W.-M.

Journal:

Year:

2012

Language:

english

File:

PDF, 619 KB

english, 2012

44

A carbonyl capture approach for profiling oxidized metabolites in cell extracts

Mattingly, Stephanie J., Xu, Tao, Nantz, Michael H., Higashi, Richard M., Fan, Teresa W.-M.

Journal:

Year:

2012

Language:

english

File:

PDF, 417 KB

english, 2012

45

Emergence and recovery response of phosphate metabolites and intracellular pH in intact Mytilus edulis as examined in situ by in vivo 31P-NMR

Teresa W-M. Fan, Richard M. Higashi, Jefferey M. Macdonald

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1991

Language:

english

File:

PDF, 1.03 MB

english, 1991

46

Temperature dependence of arginine kinase reaction in the tail muscle of live Sycionia ingentis as measured in vivo by 31P-NMR driven saturation transfer

Teresa W.-M. Fan, Richard M. Higashi, Andrew N. Lane

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1992

Language:

english

File:

PDF, 307 KB

english, 1992

47

Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes

Teresa WM Fan, Magda Kucia, Kacper Jankowski, Richard M Higashi, Janina Ratajczak, Marius Z Ratajczak, Andrew N Lane

Journal:

Molecular Cancer

Year:

2008

Language:

english

File:

PDF, 5.08 MB

english, 2008

48

Altered regulation of metabolic pathways in human lung cancer discerned by13C stable isotope-resolved metabolomics (SIRM)

Teresa WM Fan, Andrew N Lane, Richard M Higashi, Mohamed A Farag, Hong Gao, Michael Bousamra, Donald M Miller

Journal:

Molecular Cancer

Year:

2009

Language:

english

File:

PDF, 2.31 MB

english, 2009

49

A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on13C mass isotopologue profiles under non-steady-state conditions

Hunter NB Moseley, Andrew N Lane, Alex C Belshoff, Richard M Higashi, Teresa WM Fan

Journal:

Year:

2012

Language:

english

File:

PDF, 137 KB

english, 2012

50

A novel microreactor approach for analysis of ketones and aldehydes in breath

Fu, Xiao-An, Li, Mingxiao, Biswas, Souvik, Nantz, Michael H., Higashi, Richard M.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2011

Language:

english

File:

PDF, 249 KB

english, 2011

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